Osteoarthritis M15.0 715


synonyms: OA, osteoarthritis, DJD, degenerative joint disease

Osteoarthritis ICD-10

Osteoarthritis Etiology / Epidemiology / Natural History

  • Age related damage to articular cartilage and associated bony remodeling.
  • Risk Factors/etiology: age, female sex, prior joint injury/trauma, family history/genetic predisposition, obesity,  repetitive use, muscle weakness, and joint laxity
  • Prostaglandin E2 has been demonstrated in OA cartilage demonstrating that inflammation is envolved in OA.

Osteoarthritis Anatomy

  • Most commonly affects: hands, feet, knees, hips, spine.

Osteoarthritis Clinical Evaluation

  • Activity related joint pain;
  • Joint stiffness related to inactivity.

Osteoarthritis Xray / Diagnositc Tests

  • Four primary Xrays findings of osteoarthritis:
    1-loss of joint space
    2-subchondral sclerosis
    3-osteophyte formation
    4-subchondral cysts

Osteoarthritis Classification / Treatment

  • Activity modification
  • Exercise: low-impact excercise including isokinetic and isotonic strengthening improves symptoms, function and cartilge glycosaminoglycan content. (Roddy E, Rheumatology 2005;44:67)
  • Cane/walker (Blount WP, JBJS 1956;38A:695).
  • Acetaminophen / NSAIDs
  • Glucosamine sulfate / Chondroitin Sulfate:Glucosamine 1500mg daily, Chondroitin 800md daily.
  • ASU (Avocado/Soybean) generally used as an addition to glucosamine/chondroitin: ASU 300mg daily.
  • Green Tea extract
  • Corticosteriod injections
  • Viscosupplementation (Hyaluronic acid injections): Can provide up to 6 months of improvement. (Arrich J CMAJ 2005;172:1039). Side effects: injection site pain, pseudoseptic reaction, infection.
  • Weight loss: reduces risk of OA progression and improves symptoms and function (Messier SP, Arthritis Rheum 2004;50:1501).
  • Surgical Options: THA, TSA, TEA, TKA, etc

Osteoarthritis Associated Injuries / Differential Diagnosis

  • Osteoarthritis
  • Fibromyalgia
  • Psoriatic Arthritis
  • Ankylosing Spondylitis
  • Rheumatoid Arthritis

Osteoarthritis Complications

Osteoarthritis Follow-up Care

Osteoarthritis Review References