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Exertional Rhabdomyolysis

ICD-9 Classification / Treatment
Etiology / Natural History Associated Injuries / DDx
Anatomy Complications
Clinical Evaluation Follow-up Care
Xray / Diagnositc Tests Review References


Exertional Rhabdomyolysis ICD-9


Exertional Rhabdomyolysis Etiology / Epidemiology / Natural History

  • Rhabdomyolysis = muscle fibers break down and release intracellular elements into the bloodstream.  Myoglobin is release which can lead to renal failure.
  • Has been reported in college football players, nonathletes, endurance runners, endurance athletes.
  • Reported after eccentric large muscle contraction exercises such as squats

Exertional Rhabdomyolysis Anatomy


Exertional Rhabdomyolysis Clinical Evaluation

  •  Dark urine, muscle swelling, pain and weakness

Exertional Rhabdomyolysis Xray / Diagnositc Tests

  •  Serum creatine kinase and myoglobin, urine myoglobin.  Also consider serum calcium, and potassium as well as urinalysis.

Exertional Rhabdomyolysis Classification / Treatment

  • IV normal salen titrated to produce 200ml/hr to 300ml/hr urine output until creatine kinase levels normalize and myoglobinuria resolves
  • Follow closely for compartment syndrome
  • Prevention: adequate hydration, appropriate conditioning

Exertional Rhabdomyolysis Associated Injuries / Differential Diagnosis


Exertional Rhabdomyolysis Complications

  • Renal failure
  • Compartment syndrome

Exertional Rhabdomyolysis Follow-up Care

  •  Prevention: adequate hydration, proper nutrition, appropriate conditioning
  •  Protein shakes the day of workout or the day prior to workout may provide some protection from muscle injury. (Amendola, N)

Exertional Rhabdomyolysis Review References





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